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Table 4 Summary of most upregulated and downregulated gene expression

From: Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures

Th1 Th1
nitric oxide synthase 2 (iNOS) neuropeptide Y receptor 5
STAT 1 dopaminergic receptor A1
CDP-diacylglycerol synthase dopaminergic receptor D3
proteasome (prosome, macropain) alpha 6 glutamate receptor, metabotropic 7b.
proteasome subunit R-RING Na+ channel, voltage-gated, 1 alpha
P-glycoprotein, multi-drug resistance 1 K+ channel, voltage-gated, shaker related 2
Janus kinase 2 (JAK 2) hepatic nuclear factor 4 alpha
fox-1 homolog PPAR gamma
protein tyrosine kinase 2B fatty acid CoA ligase, long chain 4
caspase 7 17-beta hydroxy sterol reductase, type 1
cytosolic acyl CoA thioesterase 1 diacyl glycerol kinase beta
superoxide dismutase 2 ubiquitin-conjugating enzyme E2D 2
nitric oxide synthase 2 (iNOS) neuropeptide Y receptor 5
CDP-diacylglycerol synthase glycine receptor, alpha 1 subunit
superoxide dismutase 2 Na+ channel, voltage-gated, 1 alpha
STAT 5a testosterone 6-beta hydroxylase
P glycoprotein (multi-drug resistance) ubiquitin-conjugating enzyme E2D 2
Janus kinase 2 (JAK 2) EDG, endothelial sphingolipid GPCR
homer dopaminergic receptor D3
NF kappa B, p105 subunit glutathione S-transferase, Yc2 subunit
purinergic P2Y receptor 2 beta tubulin 2b
caspase 7 hepatic nuclear factor alpha
protein tyrosine kinase 2b chapsyn-110
Ca++ ATPase, plasma membrane 1 PPAR gamma
Th2 Th2
CDP-diacylglycerol synthase chapsyn-110
low density lipoprotein receptor 1 dopaminergic receptor A1
arginase 1 beta tubulin 2b
fox-1 homolog dopaminergic receptor D3
stress activated protein kinase alpha II Ca++ channel, voltage-gated, L type alpha 1D
K+ inwardly-rectifying channel, J3 (GIRK1) preprotachykinin A (substance P precursor)
jun B serotonergic receptor 4
purinergic P2Y receptor 2 purinergic receptor P2X, ligand-gated 3
glycine transporter 1 angiotensin receptor, type 1b
carbonic anhydrase II ubiquitin-conjugating enzyme E2D 2
CREB K+ channel, voltage-gated S1
superoxide dismutase 2 25-OH vitamin D3 24-hydroxylase