The chemokine CXCL13 is a key regulator of B cell recruitment to the cerebrospinal fluid in acute Lyme neuroborreliosis

Table 1 Clinical data and basic CSF parameters of the LNB patients

Pat. Nr.	Gender f/m	Age [y]	Clinical syndrome	Cell count [/μl]	Plasma cells [%]	Albumin quotient¹	Antibody index²
1	f	69	BS	53	15	43.9	1.7
2	m	15	CNP, M	600	0	5.4	4
3	f	70	BS	90	0	4.83	n.d.⁺
4	m	62	BS, CNP	246	16	39.7	7.3
5	f	69	BS	109	5	15.8	13.3
6	f	61	BS	217	1	37.9	40.7
7	m	66	BS, CNP	16	0	8.9	<1.5^#
8	m	67	BS, M	52	20	10.3	34
9	m	61	BS	1*	8	30.3	10.9
10	m	72	CNP	166	3	21.6	62.7
11	m	59	BS	100	0	23.4	2.8
12	m	38	M	117	11	26	168
13	m	55	BS, CNP	368	n.d.	19.1	38.6
14	m	50	CNP	12	0	4.5	7.7
15	f	46	BS	14	0	3.9	1.8
16	m	59	BS	30	0	13.2	2.5
17	f	59	BS	255	5	33.2	17.8
18	f	62	CNP, M	180	1	10.5	4.3

BS: Bannwarth's syndrome (meningopolyradiculitis), CNP: Cerebral nerve palsy (Cranial neuritis), M: Meningitis. ¹CSF/serum albumin quotient, ²B.b.-specific antibody index. * = cell count at follow up lumbar puncture (8 days later) showed 70 leucocytes/μl and an increasing antibody index (27.5). ⁺ antibody index initially not done, but on repeated lumbar puncture 13 days later, the CSF showed an B.b.-specific antibody index of 9.34 (and cell count of 102/μl). ^# antibody index at follow up 4 days later 2.1, and 12 days later 4.8 (and cell count of 13, and 17, respectively).

ISSN: 1742-2094