Skip to main content

Table 3 Protein levels of iNOS, IL-6, IL-1ß and TNF-α in microvessels after MCAO and treatment with U0126

From: Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway

Micro-vessels
  Control MCAO MCAO + U0126-0 h MCAO + U0126-6 h MCAO + U0126-12 h
iNOS (%) ± s.e.m 100 ± 7.2 144 ± 1.0* 95 ± 10# 109 ± 3.01 112 ± 8.4
IL-6 (%) ± s.e.m 100 ± 8.6 134 ± 4.4* 106 ± 7.8# 101 ± 2.7# 119 ± 3.6
IL-1ß (%) ± s.e.m 100 ± 3.1 125 ± 4.9* 113 ± 5.5# 96 ± 2.4# 122 ± 14.2
TNF-α ± s.e.m 100 ± 7.1 205 ± 12* 117 ± 11# 117 ± 7.1# 149 ± 9*
  1. Values are expressed as percentage of control and given as mean ± s.e.m, n = 5-6,
  2. *and # P < 0, 05, * = significant difference between control groups and MCAO or control and treated at 12 hours, # = significant difference between MCAO and treatment groups (starting at 0 and 6 hours).