From: Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway
 | Middle cerebral artery | Micro-vessels | Brain tissue | ||||||
---|---|---|---|---|---|---|---|---|---|
 | Control | MCAO | Treated | Control | MCAO | Treated | Control | MCAO | Treated |
iNOS(%) ± s.e.m | 100 ± 5.4 | 168 ± 7* | 139 ± 7.7 | 100 ± 11.5 | 146 ± 10* | 118 ± 13 | 100 ± 5 | 118 ± 9 | 106 ± 6 |
IL-6(%) ± s.e.m | 100 ± 3 | 180 ± 13* | 104 ± 3# | 100 ± 4.9 | 146 ± 17* | 103 ± 4 | 100 ± 8.9 | 109 ± 13 | 101 ± 12.2 |
IL-1ß(%) ± s.e.m | 100 ± 5 | 146 ± 3* | 117 ± 4.5 | 100 ± 5 | 117 ± 3.6 | 101 ± 3.8 | 100 ± 0.6 | 113 ± 4 | 102 ± 6.4 |
TNF-α ± s.e.m | 100 ± 8 | 168 ± 8.7* | 102 ± 12# | 100 ± 5 | 117 ± 3.6 | 101 ± 3.8 | 100 ± 0.6 | 113 ± 4 | 102 ± 6.4 |