Figure 4
From: Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice
Representative images of TUNEL-positive cells in post-ischemic mouse brain tissue after 60 min MCAO and 48 h reperfusion. TUNEL (apoptotic and necrotic)-positive cells (B, D) in ischemic brain tissue of the infarct border zone (penumbra) of male wild-type (C, D) and CD59a-deficient mice (A, B). A,C: staining of cell nuclei using Hoechst 33258, which stains DNA (Invitrogen, Germany).