Figure 4
From: Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death
COX-2 inhibitor mediated decrease of KA-induced activated caspase 3 in white matter and gray matter. The appearance of cells stained with the marker for cell death (activated caspase-3) was assessed in four spinal cord sections for white matter (left) and gray matter (right) with treatments of vehicle (control), kainic acid (KA) or kainic acid with the COX-2 inhibitor NS398 (KA/NS398). Error bars are SEM and P values determined by ANOVA Tukey-Kramer. This is a representative experiment which has been repeated in two other experiments.