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Table 2 Differentially expressed transcripts after 24 h stimulation of BV-2 cells with 50 μM luteolin

From: Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype

Nr ID Symbol Gene Name FC* Cov
UP-REGULATED
1 74315 Rnf145 Ring finger protein 145 2.87 11
2 76650 Srxn1 Sulfiredoxin 1 homolog 2.38 5
3 19252 Dusp1 Dual specificity phosphatase 1 2.35 10
4 12267 C3ar1 Complement component 3a receptor 1 2.30 22
5 12491 Cd36 CD36 antigen 2.28 10
6 12475 Cd14 CD14 antigen 2.25 10
7 233016 Blvrb Biliverdin reductase B 2.22 9
8 15368 Hmox1 Heme oxygenase 1 2.17 10
9 210992 Lpcat1 Lysophosphatidylcholine acyltransferase 1 2.13 11
DOWN-REGULATED
1 13198 Ddit3 DNA-damage inducible transcript 3 -5.21 11
2 12862 Cox6a2 Cytochrome c oxidase, subunit VI a, polypeptide 2 -2.89 9
3 228775 Trib3 Tribbles homolog 3 -2.62 22
4 56312 Nupr1 Nuclear protein 1 -2.36 15
5 13011 Cst7 Cystatin F -2.19 9
6 223920 Soat2 Sterol O-acyltransferase 2 -2.16 8
7 16149 Cd74 CD74 antigen -2.10 8
8 17064 Cd93 CD93 antigen -2.08 11
9 213002 Ifitm6 Interferon induced transmembrane protein 6 -2.06 8
  1. Significance analysis of triplicate microarrays was performed with a false discovery rate of 0.1% and a minimum probe coverage of 3. ID, Entrez Gene ID; FC: Fold change; Cov: probe coverage; * validated by Taqman realtime RT-PCR