Table 3 Differentially expressed transcripts after 24 h stimulation with 50 μM luteolin + 50 ng/ml LPS versus 50 ng/ml LPS
Nr | ID | Symbol | Gene Name | FC* | Cov |
|---|---|---|---|---|---|
UP-REGULATED | |||||
1 | 74315 | Rnf145 | Ring finger protein 145 | 3.27 | 11 |
2 | 210992 | Lpcat1 | Lysophosphatidylcholine acyltransferase 1 | 2.55 | 11 |
3 | 12522 | Cd83 | CD83 antigen | 2.51 | 11 |
4 | 14630 | Gclm | Glutamate-cysteine ligase, modifier subunit | 2.46 | 10 |
5 | 16889 | Lipa | Lysosomal acid lipase A | 2.31 | 6 |
6 | 56336 | B4galt5 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 | 2.30 | 8 |
7 | 14950 | H13 | Histocompatibility 13 | 2.30 | 7 |
8 | 14104 | Fasn | Fatty acid synthase | 2.28 | 4 |
9 | 12125 | Bcl2l11 | BCL2-like 11 | 2.16 | 14 |
10 | 16542 | Kdr | Kinase insert domain protein receptor | 2.16 | 9 |
11 | 216345 | Ccdc131 | Coiled-coil domain containing 131 | 2.11 | 7 |
DOWN-REGULATED | |||||
1 | 66141 | Ifitm3 | Interferon induced transmembrane protein 3 | -13.74 | 9 |
2 | 433470 | AA467197 | Expressed sequence AA467197, miR-147 | -9.32 | 9 |
3 | 16819 | Lcn2 | Lipocalin 2 | -6.87 | 10 |
4 | 14469 | Gbp2 | Guanylate binding protein 2 | -6.41 | 16 |
5 | 14962 | Cfb | Complement factor B | -5.94 | 8 |
6 | 13198 | Ddit3 | DNA-damage inducible transcript 3 | -5.58 | 11 |
7 | 16181 | Il1rn | Interleukin 1 receptor antagonist | -5.28 | 33 |
8 | 55932 | Gbp3 | Guanylate binding protein 3 | -4.72 | 10 |
9 | 56312 | Nupr1 | Nuclear protein 1 | -4.35 | 15 |
10 | 75345 | Slamf7 | SLAM family member 7 | -4.14 | 9 |
11 | 20210 | Saa3 | Serum amyloid A 3 | -3.78 | 7 |
12 | 17386 | Mmp13 | Matrix metallopeptidase 13 | -3.63 | 11 |
13 | 15439 | Hp | Haptoglobin | -3.56 | 11 |
14 | 17167 | Marco | Macrophage receptor with collagenous structure | -3.34 | 8 |
15 | 12266 | C3 | Complement component 3 | -3.29 | 6 |
16 | 12870 | Cp | Ceruloplasmin | -3.05 | 5 |
17 | 13011 | Cst7 | Cystatin F | -3.03 | 9 |
18 | 23882 | Gadd45g | Growth arrest and DNA-damage-inducible 45 gamma | -2.95 | 11 |
19 | 242341 | Atp6v0d2 | ATPase, H+ transporting, lysosomal V0 subunit D2 | -2.81 | 13 |
20 | 68774 | Ms4a6d | Membrane-spanning 4-domains, subfamily A, member 6D | -2.75 | 19 |
21 | 83673 | Snhg1 | Small nucleolar RNA host gene 1 | -2.75 | 24 |
22 | 12494 | Cd38 | CD38 antigen | -2.73 | 6 |
23 | 19655 | Rbmx | RNA binding motif protein, X chromosome | -2.73 | 11 |
24 | 56405 | Dusp14 | Dual specificity phosphatase 14 | -2.68 | 10 |
25 | 213002 | Ifitm6 | Interferon induced transmembrane protein 6 | -2.57 | 8 |
26 | 12517 | Cd72 | CD72 antigen | -2.55 | 9 |
27 | 14129 | Fcgr1 | Fc receptor, IgG, high affinity I | -2.55 | 11 |
28 | 14130 | Fcgr2b | Fc receptor, IgG, low affinity IIb | -2.48 | 27 |
29 | 231532 | Arhgap24 | Rho GTPase activating protein 24 | -2.46 | 8 |
30 | 29818 | Hspb7 | Heat shock protein family, member 7 (cardiovascular) | -2.45 | 5 |
31 | 17476 | Mpeg1 | Macrophage expressed gene 1 | -2.43 | 6 |
32 | 66222 | Serpinb1a | Serine peptidase inhibitor, clade B, member 1a | -2.41 | 10 |
33 | 78771 | Mctp1 | Multiple C2 domains, transmembrane 1 | -2.39 | 8 |
34 | 20568 | Slpi | Secretory leukocyte peptidase inhibitor | -2.39 | 9 |
35 | 12507 | Cd5 | CD5 antigen | -2.35 | 9 |
36 | 50778 | Rgs1 | Regulator of G-protein signaling 1 | -2.35 | 11 |
37 | 21897 | Tlr1 | Toll-like receptor 1 | -2.20 | 5 |
38 | 16149 | Cd74 | CD74 antigen | -2.17 | 5 |
39 | 73167 | Arhgap8 | Rho GTPase activating protein 8 | -2.13 | 8 |
40 | 15064 | Mr1 | Major histocompatibility complex, class I-related | -2.06 | 7 |
41 | 347722 | Centg2 | Centaurin, gamma 2 | -2.04 | 11 |
42 | 98365 | Slamf9 | SLAM family member 9 | -2.04 | 8 |
43 | 72999 | Insig2 | Insulin induced gene 2 | -2.00 | 8 |