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Table 1 CSF CHI3L1 levels in neurodegenerative diseases.

From: In vivo CHI3L1 (YKL-40) expression in astrocytes in acute and chronic neurological diseases

Condition (n)

Age range (median)

CHI3L1 concentration (range, ng/ml)

CHI3L1 concentration (median, ng/ml)

Healthy young controls (n = 12)

<40

67-256

109

MS (n = 10)

28-58 (48)

152-697

281

Aged healthy controls (n = 7)

60-70 (65)

139-257

218

AD (n = 10)

59-86 (75)

153-1230

212

ALS (n = 10)

32-74 (62.5)

75-769

388

Stroke (n = 10)

60-89 (72)

160-1065

359

  1. CSF samples from MS, AD, ALS, stroke and control patients were analyzed for CHI3L1 using the MicroVue CHI3L1 ELISA kit.