Figure 5From: Herpes simplex virus induces neural oxidative damage via microglial cell Toll-like receptor-2HSV-induced p38 MAPK and p42/p44 ERK1/2 activation in primary microglia is attenuated TLR2-/- mice. Microglial cell cultures from wild-type and TLR2-/- mice were infected with HSV-1 (MOI = 2) for 30 min. Cell lysates were collected and probed for total and phosphorylated p38 MAPK and p42/p44 ERK1/2.Back to article page