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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Mucopolysaccharidosis IIIB, a lysosomal storage disease, triggers a pathogenic CNS autoimmune response

Figure 3

CD8+ T-cell infiltration in the CNS of mice receiving an adoptive transfer of MPS IIIB lymphocytes. Cryostat sections of brain and spinal cord of MPS IIIB lymphocyte treated mice (2 wk pi) were assayed by immunofluorescence, using a primary antibody against mouse CD8a and a secondary antibody conjugated with Alexa Fluo 568. a. thalamus; b. brain stem; c. cerebral cortex; d. lumbar spinal cord. Yellow arrowheads: CD8+ T-cells; red arrow: meninge; D3V: dorsal 3rd ventricle. scale bar: 20 μm.

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