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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Cytosolic phospholipase A2alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice

Figure 4

cPLA 2 α regulates post-ischemic COX-2 levels. Immunofluorescence of COX-2 (green) and fluorescent Nissl dye (blue) in brain slices from cPLA2α+/+ and cPLA2α-/- mice after 2-hour MCAO, 2-hour MCAO and 2-hour reperfusion, or sham surgery. Images of the ischemic core and penumbra regions from the ipsilateral and contralateral hemispheres of each genotype are shown. Representative images, n = 3 mice of each genotype. Ipsi, ipsilateral; Contra, contralateral.

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