Effect of resveratrol on LPS-induced cytokine production. Murine primary microglial cells or astrocytes were treated with/without various concentrations of resveratrol (RV) in serum-free DMEM for 30 min followed by 0.5 μg/mL LPS for another 24 h. TNFα (A), IL-6 (C), MCP-1 (D) in supernatants and IL-1β (B) in cell lysate were detected by ELISA. Results are presented as mean ± SD for duplicate measurements from 3 independent experiments. **P < 0.01 compared with medium control or treatment with 50 μM RV alone. ## P < 0.01 compared with treatment with 0.5 μg/ml LPS.