Resveratrol inhibits activation of NF-κB by LPS. Murine primary microglial cells (A) or astrocytes (B) transfected with an NF-κB luciferase reporter plasmid and a pRL-TK-Renilla vector were treated with LPS and different concentrations of resveratrol (RV) for 16 h. Cell lysates were prepared and luciferase activities were measured. Results are presented as mean ± SD for 3 independent experiments. **p < 0.01 compared with medium control or treatment with 50 μM RV alone. #p < 0.05, ##p < 0.01 compared with treatment with LPS.