Table 2 Proportions of single Aβ peptide species secreted by non-adherent mononuclear phagocytes stimulated with polystyrene beads, acLDL or LPS (2D-Aβ-WIB, mab 1E8)

5.37-A

5.37

Aβ_1-40

63.9 ± 3.8

30.0 ± 7.0***

37.5 ± 6.5***

49.2 ± 9.5*

42.0 ± 12.0**

5.37-B

5.37

Aβ_1-42

3.7 ± 1.9

2.8 ± 0.8

3.2 ± 0.2

4.0 ± 0.1

3.3 ± 0.2

5.37-C

5.37

Aβ_1-39

1.8 ± 0.1

4.0 ± 0.8***

4.9 ± 0.4***

4.8 ± 0.6***

4.2 ± 0.9***

5.37-D

5.37

Aβ_1-38

9.6 ± 1.9

12.4 ± 1.1

13.1 ± 1.3*

13.4 ± 1.5*

11.9 ± 2.5

5.37-E

5.37

Aβ_1-37

5.7 ± 1.2

7.2 ± 1.2

8.5 ± 1.6

7.3 ± 1.2

6.8 ± 2.3

5.37-F

5.37

Aβ_1-41

2.9 ± 1.6

2.7 ± 0.6

3.0 ± 0.3

3.7 ± 0.2

2.5 ± 0.7

6.37-A

6.37

Aβ_2-40

1.7 ± 0,7

6.0 ± 1.1**

4.2 ± 0.6

2.8 ± 1.1

6.4 ± 3.1***

6.37-B

6.37

Aβ_2-42

0.6 ± 0.4

4.3 ± 1.2***

3.7 ± 0.8**

2.5 ± 1.2*

3.5 ± 1.5**

6.37-F

6.37

n. i.,

Aβ_2-40^a

8.4 ± 5.3

20.1 ± 5.9**

11.4 ± 1.7

4.4 ± 1.5

10.0 ± 2.3

6.37-G

6.37

n. i.

0.5 ± 0.4

4.7 ± 1.2***

3.8 ± 0.9***

2.6 ± 1.2*

3.4 ± 1.6**

5.45-A

5.45

n.i.,

Aβ_2-40^b

1.3 ± 0.9

5.9 ± 1.3**

6.7 ± 0.7***

5.3 ± 2.0**

6.0 ± 2.9**