Table 1 Demographic, clinical and biochemical data of subjects.
From: Serum levels of S100B and NSE proteins in Alzheimer's disease patients
Control group (N = 66) | AD patients (N = 54) | P value | |
|---|---|---|---|
Age (years) (mean ± SD) | 76.56 ± 5.46 | 77.13 ± 7.57 | 0.773 |
Gender | |||
Male (%) | 20 (30%) | 18 (33%) | 0.681 |
Female (%) | 46 (70%) | 36 (67%) | |
Education (in years) | 8.48 ± 5.24 | 5.23 ± 4.38 | 0.01 |
MMSE (mean ± SD) | 27.09 ± 2.99 | 10.98 ± 6.44 | 0.001 |
CDR (%) | |||
0 | 66 (100%) | - | 0.001 |
1 (mild) | - | 12 (22%) | |
2 (moderate) | - | 22 (41%) | |
3 (severe) | - | 20 (37%) | |
S100B (μg/l) (mean ± SD) | 0.21 ± 0.36 | 0.08 ± 0.06 | 0.008 |
NSE (μg/l) (mean ± SD) | 9.54 ± 5.28 | 9.28 ± 3.86 | 0.832 |