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Table 1 Demographic, clinical and biochemical data of subjects.

From: Serum levels of S100B and NSE proteins in Alzheimer's disease patients

  Control group
(N = 66)
AD patients
(N = 54)
P value
Age (years) (mean ± SD) 76.56 ± 5.46 77.13 ± 7.57 0.773
   Gender    
   Male (%) 20 (30%) 18 (33%) 0.681
   Female (%) 46 (70%) 36 (67%)  
Education (in years) 8.48 ± 5.24 5.23 ± 4.38 0.01
MMSE (mean ± SD) 27.09 ± 2.99 10.98 ± 6.44 0.001
CDR (%)    
   0 66 (100%) - 0.001
   1 (mild) - 12 (22%)  
   2 (moderate) - 22 (41%)  
   3 (severe) - 20 (37%)  
S100B (μg/l) (mean ± SD) 0.21 ± 0.36 0.08 ± 0.06 0.008
NSE (μg/l) (mean ± SD) 9.54 ± 5.28 9.28 ± 3.86 0.832
  1. MMSE: Mini Mental State Examination. CDR: Clinical Dementia Rating