Figure 4
The COX2 pathway is shifted towards anti-inflammatory mediators in EAE+S group. A COX2 expression measured by western blot is lower in spinal cord of animals from the EAE+S group compared to the EAE group. B Chronic stress increased levels of the anti-inflammatory prostaglandin 15d-PGJ2 in spinal cord. C. Expression of lipocalin PGD synthase, the final enzyme responsible for synthesis of 15d-PGJ2 was also higher in spinal cord of the EAE+S group. β-Actin was used as internal control and densitometric analysis of the band of interest is shown below. *p < 0,05 vs EAE;. # p < 0,05 vs Control, one way ANOVA test followed by a Newman-Keuls