Figure 3
From: Distinct modulation of microglial amyloid β phagocytosis and migration by neuropeptidesi
Microglial Aβ 1-42 degradation is not affected by neuropeptides. BV2 and N9 cells were incubated for 15 h with bradykinin (BK) (A, B) or endothelin (ET) (C, D) or somatostatin (SST) (E, F). Then, FAM-labelled Aβ was added and phagocytosis of Aβ1-42 was allowed for 30 min. Thereafter all media were removed and fresh medium was added for the indicated time periods. In order to confirm that cells were plated equally, cells were stained with Hoechst 33342 (n = 4 +/- SEM).