Figure 6From: TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after strokepSmad2 immunoreactivity is increased in the stroke penumbra and colocalizes with CD68 and GFAP. Representative images (10×) showing CD68 and GFAP colocalized with pSmad2 after stroke (image A is from a young female mouse at day 14 post stroke, image B is from a young female mouse after sham surgery). There is a qualitative increase in pSmad2 immunoflorescence in the infarcted region (outlined) with the brightest cells co-localizing with CD68 and GFAP.Back to article page