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Table 2 Pattern of the tissue response

From: Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease

 

AT8-positive

Iba1-positive

Iba1-positive

MHCII-positive

GFAP-positive

 

NFTs

microglia

phagocytes

microglia

astrocytes

WKY TG

++

++(+)

++

+++

++

SHR TG

+++

+++

+++

+

++

  1. Pattern of the tissue response on the tau-induced neurodegeneration in the terminal stage of transgenic phenotype, revealed by stereological quantification.
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Journal of Neuroinflammation

ISSN: 1742-2094