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Table 2 Gf enhancement correlates with clinical EAE parameters

From: Gadofluorine M-enhanced MRI shows involvement of circumventricular organs in neuroinflammation

 

EAE score at Gf imaging

Day of clinical onset

 

Gf lesion volume

SFO

AP

Gf lesion volume

SFO

AP

Spearman r

0.56

0.66

0.53

-0.09

-0.45

-0.35

95% CI

0.15 to 0.80

0.30 to 0.85

0.08 to 0.79

-0.54 to 0.41

-0.74 to -0.01

-0.70 to 0.14

P value

0.009

0.001

0.021

0.732

0.043

0.147

Significance

**

**

*

no

*

no

  1. Correlation of clinical EAE parameters to total Gf lesion volume in T1-weighted images and Gf enhancement (mean intensity ratio) in the subfornicular organ (SFO) and the area postrema (AP). Correlations for other circumventricular organs were not statistically significant.
  2. *: P value < 0.05; **: P value < 0.01; CI: confidence interval