Skip to main content

Table 2 Details of hmSOD1 rats per disease stages

From: Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosis

Disease Stage Number of Animals
(male, female)
Average Age in Days +/- SD Average Recent Weight Change* in g/day +/- SD Average Motor Score** +/- SD
Early Pre-Clinical 4 (3,1) 70.5 +/- 6.6 3.2 +/- 1.5 8
Late Pre-Clinical 5 (4,1) 90.8 +/- 1.6 2.7 +/- 0.9 8
Clinical Onset 5 (4,1) 105.2 +/- 5.0 -0.3 +/- 1.0 8
End-Stage 6 (4,2) 119.5 +/- 5.5 -10.0 +/- 3.9 3.5 +/- 1.0
  1. Number, age, and clinical phenotype of hmSOD1 rats in each disease stage that were used for histological analysis. SD represents standard deviation. *Recent Weight change was recorded over a 10 day period. **See Table 1 for criteria of motor scoring.