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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Microglial activation state exerts a biphasic influence on brain endothelial cell proliferation by regulating the balance of TNF and TGF-β1

Figure 2

Quantification of BEC proliferation in response to cytokines. BEC proliferation was examined over 16 hours in the presence of different concentrations of the cytokines, IFN-α (A), IFN-γ (B), IL-6 (C), TGF-β1 (D), or TNF (E). BEC proliferation is expressed as the percentage of BEC that incorporated BrdU; all points represent the mean ± SEM of 4 experiments. Note that BEC proliferation was significantly stimulated by TNF, and inhibited by TGF-β1. p < 0.05.

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