Skip to main content
Figure 4 | Journal of Neuroinflammation

Figure 4

From: Microglial activation state exerts a biphasic influence on brain endothelial cell proliferation by regulating the balance of TNF and TGF-β1

Figure 4

Function-blocking experiments to examine the role of TNF and TGF-β1 in mediating the effects of MG-CM. BEC proliferation is expressed as the percentage of BEC that incorporated BrdU; all points represent the mean ± SEM of 4 experiments. Note that the inhibitory influence of resting MG-CM was partially relieved by TGF-β1 antibodies (A) and conversely, the mitogenic influence of activated MG-CM was abrogated by anti-TNF antibodies (B). p < 0.05.

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094