Figure 4

EAE results in a significant decrease in spinal cord VEGF. Spinal cords were harvested during the relapse phase of EAE, divided into cervical, thoracic and lumbar areas, homogenized and measured using a specific rat VEGF ELISA kit. There is a significant decrease in VEGF in the cervical and lumbar areas in EAE rats compared to naïve controls. * p < 0.05, **p < 0.01 n = 5 rats per group