Vascular meteorin expression is affected during EAE in the lumbar spinal cord. Meteorin immunoreactivity is closely associated with many blood vessels and appears to completely surround blood vessels in naive rats (A, arrowhead). In addition there are a few branched cells in the parenchyma expressing meteorin, which resemble astrocytes (arrows, A). In relapsing EAE rats there are breaks in the blood vessel (asterisks, B) associated meteorin in the white matter of the lumbar spinal cord. scale bar 50 μm.