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Table 3 Increased blood vessels during EAE

From: Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions

   CD31 Collagen IV
   naive EAE naive EAE
Lumbar WM 3.1 ± 0.1* 7.7 ± 1.2 2.8 ± 0.5** 8.7 ± 1.2
  GM 6.7 ± 0.4 ** 13.0 ± 1.4 8.8 ± 1.6** 16 ± 1.5
Thoracic WM 2.9 ± 0.2** 5.9 ± 0.6 3.1 ± 0.2** 6.9 ± 0.6
  GM 6.5 ± 0.7** 13 ± 1.2 9.2 ± 1.3* 17 ± 1.8
  1. * p < 0.05 compared to EAE
  2. **p < 0.01 compared to EAE
  3. Number of vessels counted using a 40× microscope objective