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Table 3 Increased blood vessels during EAE

From: Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions

  

CD31

Collagen IV

  

naive

EAE

naive

EAE

Lumbar

WM

3.1 ± 0.1*

7.7 ± 1.2†

2.8 ± 0.5**

8.7 ± 1.2

 

GM

6.7 ± 0.4 **

13.0 ± 1.4

8.8 ± 1.6**

16 ± 1.5

Thoracic

WM

2.9 ± 0.2**

5.9 ± 0.6

3.1 ± 0.2**

6.9 ± 0.6

 

GM

6.5 ± 0.7**

13 ± 1.2

9.2 ± 1.3*

17 ± 1.8

  1. * p < 0.05 compared to EAE
  2. **p < 0.01 compared to EAE
  3. †Number of vessels counted using a 40× microscope objective
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Journal of Neuroinflammation

ISSN: 1742-2094