Figure 1

GTS improves LPS-associated anorexia and weight loss. Mice were administered orally with GTS at a dosage of 200 mg.kg^-1 which was dissolved in saline once daily for 7 days prior to and on the same day of LPS injection. Immediately following the final injection, mice also received either an i.p. injection of sterile endotoxin-free saline or LPS (0.8 mgkg^-1). The 22-h change in food intake (Figure.1A) and body weight loss (Figure.1B) following LPS administration were measured. The data are expressed as mean ± SEM. For statistical significance, a: p < 0.01 compared with the vehicle/saline group, b: p < 0.05 compared with the vehicle/LPS group. c: p < 0.01 compared with the LPS/GTS group.