Figure 3
From: Wallerian degeneration: the innate-immune response to traumatic nerve injury
The time course of cytokine protein secretion during normal Wallerian degeneration. Nerve segments located 5 millimeters distal to lesion sites were removed from wild-type mice at the indicated times and used to condition medium with secreted cytokine proteins that were detected and quantified by ELISA. Values are presented as percentage of maximum secretion which is defined 100% (after [60, 86]). The secretion of IL-1α is detected within 6 hours after the injury; not shown here since the method of detection was by a bioassay [87].