Vascular endothelial growth factor-A and chemokine ligand (CCL2) genes are upregulated in peripheral blood mononuclear cells in Indian amyotrophic lateral sclerosis patients

Table 2 Crude and adjusted OR for VEGF-A mRNA

	OR (95% CI)^†	p*	Adj. OR (95% CI)^‡	p*
VEGF-A mRNA
Smoking	0.8 (0.2-4.3)	0.8	1.1 (0.2-6.3)	0.8
Alcohol consumption	1.0 (0.2-4.3)	0.9	0.9 (0.2-4.5)	0.9
Meat consumption	0.8 (0.2-3.0)	0.8	0.8 (0.2-3.3)	0.8
Never smoking/	1.0		1.0
Nonalcoholic/
Vegetarian**

† Univariate logistic regression was used to calculate crude OR. ‡ Multivariate logistic regression was used to adjust the effect of smoking on VEGF-A mRNA levels with alcohol and meat consumption as covariates. Likewise, effect of alcohol and meat consumption on VEGF-A is also adjusted for covariates. *χ² (chi square test) was used to test the level of significance. ** Never smoking, nonalcoholic and vegetarian diet is considered as reference group. VEGF-A, vascular endothelial growth factor-A; OR, odds ratio; CI, confidence interval; Adj, adjusted.

ISSN: 1742-2094