Gelsolin decreases caspase-3 activities in brain of mice following burn injury. A. Immunofluorescent staining of caspase-3 in striatum of brain 24 h postburn; B. Immunohistochemistry of caspase-3 positive cells in the cortex and hippocampus (hippo) from mice under gelsolin treatments. C. Time course of caspase-3 activity in brain as assayed by colorimetry. *P < 0.05 and **P < 0.01 vs. sham-injured mice; #p < 0.05 and ##p < 0.01 vs. placebo mice by ANOVA, Newman-Keuls post-hoc test. Data are means ± SD for n = 6-8.