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Table 1 Circulating levels of gelsolin (pg/ml) after exogenous gelsolin administration in mice after burn injury.

From: Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury

group

0 h

8 h

24 h

48 h

72 h

control

1294 ± 113

1295 ± 81

1276 ± 77

1297 ± 69

1229 ± 50

sham

1295 ± 111

1273 ± 145

1284 ± 96

1290 ± 135

1292 ± 68

burn+placebo

1136 ± 52

407 ± 57*

484 ± 117*

559 ± 106*

529 ± 169*

burn+Gsn-L

1216 ± 52

662 ± 67*#

862 ± 67*#

803 ± 197*#

817 ± 125*#

burn+Gsn-H

1193 ± 104

851 ± 32*#+

923 ± 63*#

956 ± 87*#+

844 ± 128*#

  1. *P < 0.05 vs. the sham-injured group; #p < 0.05 vs. the placebo group; +p < 0.05 vs. the Gsn-L group by ANOVA, Newman-Keuls post-hoc test. Data are means ± SD for n = 6-8.
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Journal of Neuroinflammation

ISSN: 1742-2094