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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Central administration of insulin-like growth factor-I decreases depressive-like behavior and brain cytokine expression in mice

Figure 1

IGF-I displays anti-depressant activity in the presence or absence of LPS. IGF-I (1000 ng) or (PBS) was administered i.c.v. 30 min before i.c.v. PBS or LPS (10 ng). Depressive-like behavior was assessed as immobility in the TST to define the effect of IGF-I (A), fluoxetine and desipramine (B) on depressive-like behavior. n = 16 to 19 per treatment for data in (A) and n = 8 for 9 for the data in (B)

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