Figure 3

IGF-I increases BDNF mRNA transcripts in the presence or absence of LPS. Steady-state mRNA expression for the two 3' classes of IGF-I (A, B) and two distinct BDNF transcripts (C, D) was quantified by real-time rtPCR. Expression was relative to GAPDH, which was used as a housekeeping control gene. n = 10 to 12 per treatment