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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy

Figure 2

Lack of microglia in the deep layer of the central avascular zone in OIR at P14. Flat mounts (A - D) and cryosections (E, F) show resting microglial cells with ramified processes in the central zone of the deep retinal layer (d) expressing GFP (green) under the control of the Cx3cr1 promoter. Large, blurred, green dots are microglial cells of the superficial layer (s). Note that the microglial cell density in the deep layer is much smaller at P14 compared to P12. Vessels of the deep vascular layer are stained with lectin (red). No vessels are visible in P12 and P14 OIR images as these images are taken from within the avascular central zone of the retina. Vitreous (v), choroid (c).

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