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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy

Figure 5

Distribution of retinal microglia at vascular tufts at P17. Vascular tufts and other vessels (lectin staining, red) are located at the border of the vascularized and the avascular central zone in the superficial layer (s). Microglial cells (GFP, green) near vascular tufts are not activated as they are ramified and not positive for lectin. Flat mounts show a rather even distribution of microglia. Activated microglia were found in the central avascular zone (A). Yellow staining in the sections (C and D) comes from super-position of microglia and endothelial cells but not from microglia activation. Arrow heads point to hyalocytes in the vitreous (v). E and F are the same as C and D, respectively, with the red channel omitted.

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