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Table 1 NO production by cytokines and LPS in different glial cell types

From: Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA2-IIA expression in astrocytes and microglia

Cell types

(number)

Con

TNFα+

IL1β

IFNγ

TNFα+IL1β

+ IFNγ

LPS

LPS+

IFNγ

BV-2 (1 × 105)

-

-

31.0 ± 0.5

69.5 ± 2.1

12.3 ± 2.4

79.1 ± 2.5

HAPI (1 × 105)

-

-

17.2 ± 0.5

22.4 ± 0.5

12.9 ± 0.9

39.9 ± 0.7

DITNC (1 × 105)

-

-

-

9.0 ± 0.2

-

-

RPA (3 × 105)

-

-

-

4.6 ± 1.2

-

-

  1. Results are expressed as NO in μM and are means ± SD from three experiments.
  2. RPA, rat primary astrocytes
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Journal of Neuroinflammation

ISSN: 1742-2094