Change in mRNA expression in cortical explants among mice. Change in CD74 and antisecretory factor (ASF) mRNA in cortical explants in mouse strains. RNA was isolated from freshly resected cortical tissue (baseline) and cortical explants after incubation for 4.5 hours. Transcript levels were referenced to β-actin mRNA levels. Values were expressed as fold difference relative to baseline + SEM. Pooled cDNA from SJL/J (n = 11), C57BL/6J (7), and BALB/cJ (11) mice were measured in replicates of at least three. * = P < 0.05 and ** = P < 0.01, relative to baseline, unpaired t test.