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Table 2 Differentially expressed transcripts after 6 h stimulation of BV-2 cells with 20 μM curcumin

From: Curcumin is a potent modulator of microglial gene expression and migration

Nr ID Symbol Gene Name FC
UP-REGULATED
1 80883 Ntng1 Netrin G1 313.0
2 18613 Pecam1 Platelet/endothelial cell adhesion molecule 1 42.8
3 13388 Dll1 Delta-like 1 35.5
4 12824 Col2a1 Collagen, type II, alpha 1 21.6
5 14103 Fasl Fas ligand (TNF superfamily, member 6) 12.8
6 12653 Chgb Chromogranin B 11.9
7 66184 Rps4y2 Ribosomal protein S4, Y-linked 2 9.7
8 69816 Perp1 RIKEN cDNA 2010001M09 gene 9.7
9 16992 Lta Lymphotoxin A 9.4
10 19206 Ptch1 Patched homolog 1 5.9
11 19013 Ppara Peroxisome proliferator activated receptor alpha 4.6
12 109685 Hyal3 Hyaluronoglucosaminidase 3 4.5
13 20997 T Brachyuri 4.2
14 17246 Mdm2 Transformed mouse 3T3 cell double minute 2 3.1
15 14102 Fas Fas 2.8
16 14183 Fgfr2 Fibroblast growth factor receptor 2 2.7
17 13645 Egf Epidermal growth factor 2.2
18 14179 Fgf8 Fibroblast growth factor 8 2.1
19 20655 Sod1 Superoxide dismutase 1 2.1
20 14526 Gcg Glucagon 2.0
DOWN-REGULATED
1 24088 Tlr2 Toll-like receptor 2 -6.9
2 18505 Pax3 Paired box gene 3 -6.6
3 14281 Fos FBJ osteosarcoma oncogene -4.4
4 11622 Ahr Aryl-hydrocarbon receptor -4.1
5 16835 Ldlr Low density lipoprotein receptor -3.8
6 13654 Egr2 Early growth response 2 -3.5
7 68010 Bambi BMP and activin membrane-bound inhibitor -3.3
8 12048 Bcl2l1 BCL2-like 1 -3.3
9 19225 Ptgs2 Prostaglandin-endoperoxide synthase 2 -3.0
10 20296 Ccl2 Chemokine (C-C motif) ligand 2 -2.8
11 12393 Runx2 Runt related transcription factor 2 -2.8
12 17311 Kitl Kit ligand -2.4
13 16869 Lhx1 LIM homeobox protein 1 -2.4
14 12977 Csf1 Colony stimulating factor 1 -2.4
15 20528 Slc2a4 Solute carrier family 2, member 4 -2.2
  1. Significance analysis of triplicate microarrays was performed with a false discovery rate of 0.1%. ID, Entrez Gene ID; FC: Fold change.