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Table 2 Serum and CSF TNFα after ICV administration of LPS in rats

From: Lipopolysaccharide modulates astrocytic S100B secretion: a study in cerebrospinal fluid and astrocyte cultures from rats

 

Control

LPSb

p

Serum (30 min)

0.7 ± 0.3

121.6 ± 40.0

0.001*

Serum (24 h)

1.1 ± 0.3

1.0 ± 0.3

0.945

CSF (30 min)

38.8 ± 9.8

75.1 ± 24.9

0.215

CSF (24 h)

1.7 ± 1.2

19.6 ± 4.5

0.006*

  1. Values are mean (pg/mL) ± standard error (n = 5). Statistical analysis was performed using Student's t test, * indicates p < 0.05; b 25 μg