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Table 2 Serum and CSF TNFα after ICV administration of LPS in rats

From: Lipopolysaccharide modulates astrocytic S100B secretion: a study in cerebrospinal fluid and astrocyte cultures from rats

  Control LPSb p
Serum (30 min) 0.7 ± 0.3 121.6 ± 40.0 0.001*
Serum (24 h) 1.1 ± 0.3 1.0 ± 0.3 0.945
CSF (30 min) 38.8 ± 9.8 75.1 ± 24.9 0.215
CSF (24 h) 1.7 ± 1.2 19.6 ± 4.5 0.006*
  1. Values are mean (pg/mL) ± standard error (n = 5). Statistical analysis was performed using Student's t test, * indicates p < 0.05; b 25 μg