Figure 8From: Inhibitory effect of a tyrosine-fructose Maillard reaction product, 2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells Schematic representation of a functional pathway of 2,4-bis( p -hydroxyphenyl)-2-butenal action. 2,4-Bis(p-hydroxyphenyl)-2-butenal blocks NF-κB- and STAT3-mediated upregulation of amyloidogenesis and neuro-inflammation induced by LPS.Back to article page