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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment

Figure 5

Morphological characteristics of activated astrocytes in aged hippocampus. Higher magnification imaging revealed a stellate morphology and low level of GFAP immunoreactivity in hippocampal astrocytes of adult rats. In hippocampus of both cognitively intact and cognitively impaired aged rats, astrocytes exhibited intense GFAP immunoreactivity and adopted a highly ramified morphology with hypertrophic processes, while maintaining spatial compartmentalization.

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