| CA1 | CA3 | DG | synaptosomes (whole-hippocampus) | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  | Aged | Aged |  |  | Aged | Aged |  |  | Aged | Aged |  |  | Aged | Aged |
Gene | Adult | Aged | Intact | Impaired | Adult | Aged | Intact | Impaired | Adult | Aged | Intact | Impaired | Adult | Aged | Intact | Impaired |
C1s | 100 ± 2.8 | 121 ± 6.1 | 125 ± 11.7 | 118 ± 6.6 | 100 ± 7.8 | 156 ± 7.6 | 159 ± 13.4 | 153 ± 9.3 | 100 ± 6.1 | 122 ± 4.8 | 117 ± 5.7 | 125 ± 6.9 | 100 ± 21.7 | 184 ± 21.8 | 182 ± 28.6 | 186 ± 35.3 |
C3 | 100 ± 6.6 | 200 ± 10.9 | 207 ± 16.4 | 194 ± 15.0 | 100 ± 7.9 | 196 ± 10.8 | 222 ± 17.8 | 178 ± 10.7 | 100 ± 8.1 | 169 ± 7.2 | 152 ± 10.2 | 181 ± 8.3 | 100 ± 23.2 | 347 ± 35.7 | 340 ± 27.6 | 355 ± 74.4 |
Serping1 | 100 ± 7.4 | 203 ± 13.4 | 218 ± 14.6 | 192 ± 20.2 | 100 ± 7.3 | 227 ± 11.5 | 252 ± 17.4 | 209 ± 13.1 | 100 ± 4.8 | 154 ± 6.3 | 149 ± 9.4 | 158 ± 8.7 | 100 ± 6.9 | 271 ± 12.4 | 279 ± 19.9 | 263 ± 15.5 |
Cd74 | 100 ± 7.7 | 561 ± 33.3 | 566 ± 44.5 | 558 ± 47.9 | 100 ± 10.9 | 361 ± 20.5 | 388 ± 37.6 | 340 ± 21.2 | 100 ± 7.7 | 243 ± 17.2 | 233 ± 36.7 | 249 ± 18.2 | 100 ± 28.8 | 658 ± 48.9 | 679 ± 46.7 | 635 ± 95.8 |
C4a | 100 ± 7.1 | 177 ± 7.0 | 167 ± 11.1 | 185 ± 8.6 | 100 ± 4.8 | 151 ± 4.6 | 158 ± 6.2 | 147 ± 6.2 | 100 ± 9.7 | 135 ± 10.3 | 117 ± 15.2 | 147 ± 13.0 | 100 ± 17.7 | 418 ± 44.6 | 383 ± 31.6 | 459 ± 88.3 |
Ccr5 | 100 ± 5.2 | 108 ± 5.1 | 106 ± 5.2 | 110 ± 7.8 | 100 ± 3.1 | 121 ± 6.3 | 117 ± 7.3 | 125 ± 10.3 | 100 ± 6.9 | 99 ± 7.0 | 88 ± 7.1 | 106 ± 10.4 | 100 ± 17.9 | 196 ± 23.0 | 172 ± 18.8 | 220 ± 41.8 |
Cp | 100 ± 5.4 | 93 ± 8.2 | 93 ± 6.9 | 93 ± 13.5 | 100 ± 3.9 | 156 ± 6.3 | 164 ± 9.2 | 150 ± 8.4 | 100 ± 9.2 | 110 ± 8.0 | 118 ± 13.7 | 103 ± 9.8 | 100 ± 10.8 | 167 ± 17.1 | 192 ± 28.6 | 146 ± 18.4 |
Ctse | 100 ± 8.0 | 145 ± 10.2 | 141 ± 13.7 | 148 ± 14.4 | 100 ± 9.8 | 175 ± 7.4 | 173 ± 13.9 | 177 ± 8.7 | 100 ± 6.8 | 148 ± 6.8 | 140 ± 11.3 | 154 ± 8.4 | 100 ± 21.0 | 169 ± 12.0 | 181 ± 19.8 | 156 ± 11.4 |
Erbb3 | 100 ± 2.7 | 134 ± 5.1 | 143 ± 7.5 | 128 ± 6.5 | 100 ± 8.1 | 120 ± 5.1 | 128 ± 9.1 | 114 ± 5.6 | 100 ± 7.5 | 140 ± 7.8 | 129 ± 10.9 | 147 ± 10.3 | 100 ± 5.4 | 128 ± 4.0 | 126 ± 6.5 | 130 ± 4.6 |
Fcgr2b | 100 ± 3.2 | 108 ± 7.9 | 103 ± 6.4 | 112 ± 13.0 | 100 ± 9.0 | 161 ± 5.2 | 163 ± 12.0 | 160 ± 3.6 | 100 ± 4.2 | 124 ± 11.0 | 125 ± 19.8 | 123 ± 13.2 | 100 ± 20.8 | 196 ± 15.4 | 208 ± 22.6 | 182 ± 21.2 |
Fcgr2a | 100 ± 4.4 | 119 ± 4.8 | 116 ± 3.8 | 120 ± 7.7 | 100 ± 5.2 | 130 ± 4.2 | 130 ± 6.4 | 130 ± 5.9 | 100 ± 5.1 | 115 ± 3.8 | 109 ± 5.0 | 120 ± 5.0 | 100 ± 15.2 | 145 ± 11.4 | 143 ± 10.7 | 147 ± 22.8 |
Hla-dmb | 100 ± 4.6 | 137 ± 4.6 | 133 ± 5.2 | 140 ± 7.3 | 100 ± 3.9 | 137 ± 3.7 | 139 ± 5.9 | 135 ± 4.9 | 100 ± 7.4 | 126 ± 4.4 | 115 ± 6.6 | 133 ± 4.7 | 100 ± 3.3 | 164 ± 8.3 | 157 ± 13.7 | 172 ± 8.4 |
Hla-dra | 100 ± 7.9 | 404 ± 19.0 | 418 ± 28.1 | 395 ± 26.5 | 100 ± 14.7 | 302 ± 23.4 | 325 ± 47.0 | 285 ± 23.4 | 100 ± 9.7 | 181 ± 22.4 | 190 ± 43.4 | 175 ± 26.4 | 100 ± 24.0 | 630 ± 51.8 | 676 ± 67.9 | 575 ± 79.8 |
Hsbp1 | 100 ± 12.8 | 168 ± 9.6 | 165 ± 14.0 | 170 ± 13.6 | 100 ± 8.7 | 209 ± 11.0 | 225 ± 18.7 | 197 ± 13.0 | 100 ± 9.5 | 109 ± 11.5 | 80 ± 14.2 | 130 ± 13.8 | 100 ± 17.7 | 287 ± 25.1 | 313 ± 30.1 | 258 ± 40.9 |
Icam1 | 100 ± 5.5 | 155 ± 7.6 | 168 ± 11.9 | 146 ± 9.4 | 100 ± 5.6 | 143 ± 4.2 | 164 ± 13.3 | 131 ± 5.7 | 100 ± 12.2 | 102 ± 6.5 | 100 ± 13.5 | 102 ± 6.5 | 100 ± 11.1 | 146 ± 11.8 | 145 ± 16.7 | 147 ± 18.3 |
Lgals3 | 100 ± 4.9 | 264 ± 16.6 | 262 ± 21.4 | 266 ± 24.9 | 100 ± 7.3 | 198 ± 12.6 | 218 ± 16.3 | 184 ± 17.4 | 100 ± 10.5 | 184 ± 12.9 | 163 ± 10.0 | 200 ± 20.2 | 100 ± 21.4 | 342 ± 34.1 | 368 ± 54.6 | 303 ± 39.2 |
Hla-drb1 | 100 ± 11.0 | 713 ± 57.0 | 712 ± 96.9 | 713 ± 73.8 | 100 ± 9.7 | 439 ± 34.8 | 477 ± 73.9 | 412 ± 30.1 | 100 ± 14.1 | 291 ± 40.2 | 225 ± 44.4 | 342 ± 59.0 | 100 ± 7.6 | 1050 ± 67.3 | 1070 ± 97.4 | 1026 ± 100.2 |
S100a6 | 100 ± 2.8 | 203 ± 11.5 | 200 ± 16.2 | 206 ± 16.9 | 100 ± 7.5 | 221 ± 13.4 | 248 ± 20.9 | 202 ± 15.5 | 100 ± 16.3 | 110 ± 8.3 | 88 ± 15.5 | 123 ± 7.4 | 100 ± 9.0 | 152 ± 13.1 | 161 ± 24.3 | 145 ± 15.5 |
Tlr2 | 100 ± 6.3 | 106 ± 5.7 | 109 ± 9.8 | 104 ± 7.2 | 100 ± 11.2 | 154 ± 9.6 | 166 ± 18.9 | 146 ± 9.7 | 100 ± 16.6 | 172 ± 18.8 | 166 ± 36.7 | 176 ± 22.7 | 100 ± 13.0 | 164 ± 11.3 | 155 ± 19.2 | 173 ± 12.9 |
Tlr4 | 100 ± 2.7 | 135 ± 8.1 | 118 ± 12.8 | 143 ± 9.7 | 100 ± 8.4 | 196 ± 9.5 | 200 ± 19.7 | 193 ± 9.6 | 100 ± 8.7 | 119 ± 4.0 | 118 ± 5.9 | 120 ± 5.7 | 100 ± 8.3 | 151 ± 10.1 | 141 ± 4.9 | 160 ± 19.7 |
Tlr7 | 100 ± 3.5 | 134 ± 6.5 | 134 ± 17.2 | 135 ± 3.9 | 100 ± 8.1 | 173 ± 5.0 | 174 ± 9.6 | 172 ± 5.7 | 100 ± 11.6 | 94 ± 7.6 | 95 ± 11.6 | 93 ± 10.7 | 100 ± 13.3 | 169 ± 11.3 | 165 ± 16.6 | 173 ± 16.5 |