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Figure 4 | Journal of Neuroinflammation

Figure 4

From: LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury

Figure 4

IRF3 activity is enhanced following MCAO in LPS-preconditioned mice. Nuclear protein obtained from ipsilateral cortex post 60 min MCAO analyzed using an IRF3 activity ELISA (Active Motif, Inc.) revealed a significant increase in IRF3 activity in LPS-preconditioned (0.8 mg/kg) mice. Two-way ANOVA, Bonferroni Post Hoc, LPS vs. saline, *p < 0.05, n ≥ 4 per treatment.

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