Table 1 Moser-Raymond Severity Scoring System: The scoring system used in this analysis to determine the clinical status of patients with ALD was previously developed by Moser and Raymond [17]
From: Chitotriosidase as a biomarker of cerebral adrenoleukodystrophy
Hearing/auditory processing problems 1 | 1 |
Aphasia/apraxia | 1 |
Loss of communication | 3 |
Vision impairment/fields cut | 1 |
Cortical blindness | 2 |
Swallowing difficulty or other central nervous system dysfunction | 2 |
Tube feeding | 2 |
Running difficulties/hyper-reflexia | 1 |
Walking difficulties/spasticity/spastic gait (no assistance) | 1 |
Spastic gait (needs assistance) | 2 |
Wheelchair required | 2 |
No voluntary movement | 3 |
Episodes of incontinency | 1 |
Total incontinency | 2 |
Nonfebrile seizures | 1 |
Possible Total | 25 |