Figure 2From: Post-traumatic hypoxia exacerbates neurological deficit, neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury Spontaneous movement is only reduced after traumatic axonal injury with additional hypoxia. Distance travelled (metres) was measured for 5 min as indicative of voluntary mobility in a novel open space. Diagrams depict: (A) Sham, (B) TAI, and (C) TAI+Hx. * indicates significant differences between testing at the pre-injury (Pre) or post-injury at days 3, 6 and 14. Distance travelled is shown as mean ± SEM, n = 10 per group per time point. Note the significant reduction in walking distance in TAI+Hx rats at 3 and 6 days as compared to TAI and sham rats. Data was analysed by 1-way ANOVA with Bonferroni post hoc test, with a p-value of < 0.05 considered significant.Back to article page