CCL20 is up-regulated in spleen 24 hours after mild TBI. PCR super array analysis was performed to analyze the gene expression in spleen tissues following TBI. The histograms show the mRNA expressional changes of different cytokines, chemokines and their receptors 24 hours after TBI. A: The up-regulated genes: CCL20 mRNA increased 5-fold in TBI animals compared to the sham animals. B: The down-regulated genes with 2-fold or more down-regulation.