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Figure 8 | Journal of Neuroinflammation

Figure 8

From: Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis

Figure 8

Immunofluorescence staining for CD3 and CD20 in spinal cord slices from vehicle-administered (A and B, respectively) and diazoxide-treated EAE mice (C and D, respectively). Bottom panel shows higher magnification of CD3-positive cells (C). Upon quantification, no significant differences between vehicle- and diazoxide-treated mice were observed for the numbers of CD3- and CD20-positive cells in any of the spinal cord regions analyzed (E and F, respectively). Results are expressed as mean ± SEM. n (animals) per group ≥ 6. Slices analyzed per animal and section ≥ 3. Scale bar = 100 μm.

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