| N° animals |  |  | Mean clinical score | Area under the curve (AUC) |  |
---|---|---|---|---|---|---|
 |  | N° EAE death | Days of treatment | Mean | Maximal grade |  |
Vehicle | Â | Â | Â | Â | Â | Â |
   Exp 1 | 11 | 1 | 15 | 3.1 ± 0.1 | 4.1 ± 0.4 | 43.9 ± 4.7 |
   Exp 2 | 8 | 0 | 15 | 3.3 ± 0.2 | 4.4 ± 0.1 | 48.3 ± 2.0 |
   Exp 3 | 7 | 1 | 15 | 3.5 ± 0.2 | 4.7 ± 0.2 | 56.0 ± 4.4 |
Diazoxide | Â | Â | Â | Â | Â | Â |
   Exp 1 | 11 | 0 | 15 | 1.9 ± 0.1*** | 2.7 ± 0.3* | 28.3 ± 4.4* |
   Exp 2 | 9 | 0 | 15 | 2.6 ± 0.1** | 3.8 ± 0.2* | 37.2 ± 3.1* |
   Exp 3 | 7 | 0 | 15 | 2.6 ± 0.1*** | 3.5 ± 0.5* | 36.9 ± 5.1* |