CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease

Table 1 BAb administration increases 6-OHDA-induced dopamine deficiency in ipsilateral striatum.

Groups	Content (ng/g Wet weight of tissue)
	DA	DOPAC	HVA
6-OHDA/Veh	1765.0 ± 235.6	894.1 ± 94.7	598.8 ± 103.6
6-OHDA/CAb	1674.0 ± 174.9	836.7 ± 72.3	551.7 ± 121.5
6-OHDA/BAb	37.6 ± 7.8 ***	24.2 ± 3.2 ***	16.7 ± 2.3 **
p < 0.01, *p < 0.001 compared to the 6-OHDA/Veh and 6-OHDA/CAb groups (n = 5 per group)

Results are expressed as mean ± S.E.M. (ng/g WW) of total protein. Data are shown only for ipsilateral (right) side of striatum. Statistical analysis was performed by two-way ANOVA. ** p < 0.01, *** p < 0.001 as compared to 6-OHDA/Veh lesion group.

ISSN: 1742-2094